Efinaconazole
商品编号：
TS2330
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详细介绍
l 基本信息 |
产品名称 | Efinaconazole(艾菲康唑) |
一般描述 | Efinaconazole is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. |
别 称 | KP-103; (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol |
纯 度 | ≥99.0%(HPLC) | CAS NO. | 164650-44-6 |
分子式 | C18H22F2N4O | 分子量 | 348.39 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至米色固体 |
溶解性(25°C) | DMSO | ≥45mg/ml |
乙醇 | ≥45mg/ml |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC under the name Jublia. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
