产品名称

Diaveridine(敌菌净)

一般描述

Diaveridine is coccidiostat with anti-parasitic activity and also a dihydrofolate reductase (DHFR) inhibitor preventing folic acid synthesis in species of Pneumocystis.

别 称

AI3-23935, CCRIS-3784; 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

纯 度

≥98.0%(HPLC)

CAS NO.

5355-16-8

分子式

C¹³H¹⁶N⁴O²

分子量

260.29

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至黄色固体

溶解性(25°C)

DMSO

≥15mg/ml

l  生物学信息

生物活性/药理作用

Diaveridine is an aminopyrimidine in which the pyrimidine ring carries amino substituents at C-2 and C-4 and a 3,4-dimethoxybenzyl group at C-5. A folic acid antagonist, it is used as a synergist with sulfonamides against the parasitic Eimeria species. It has a role as an antiparasitic agent.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov