产品名称

Alectinib hydrochloride(艾乐替尼盐酸盐)

一般描述

Alectinib hydrochloride is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase.

别 称

AF802 hydrochloride

纯 度

≥98.0%(HPLC)

CAS NO.

1256589-74-8

分子式

C³⁰H³⁵ClN⁴O²

分子量

519.08

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

Slightly soluble

乙醇

Insoluble

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Alectinib hydrochloride is a hydrochloride obtained by combining alectinib with one molar equivalent of hydrochloric acid. Used for the treatment of patients with anaplastic lymphoma kinase-positive, metastatic non-small cell lung cancer. It has a role as an antineoplastic agent and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It contains an alectinib(1+).

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov