产品名称

Estropipate

一般描述

Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis.

别 称

3-(Sulfooxy)-estra-1,3,5(10)-trien-17-one: piperazine (1:1), Estrone sulfate piperazine salt, Estropipate, Harmogen, Ogen

纯 度

≥98.0%(HPLC)

CAS NO.

7280-37-7

分子式

C²²H³²N²O⁵S

分子量

436.56488

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至褐色固体

溶解性(25°C)

DMSO

≥50mg/ml

l  生物学信息

生物活性/药理作用

Estropipate is a natural estrogenic substance composed of estrone sulfate and piperazine. Estropipate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the tranion of genes involved in the functioning of the female reproductive system and secondary sex characteristics.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov