产品名称

Bromopyruvic acid(3-溴丙酮酸)

一般描述

Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.

别 称

3-Bromopyruvic acid, 3-Bromopyruvate

纯 度

≥98.0%(GC)

CAS NO.

1113-59-3

分子式

C³H³BrO³

分子量

166.96

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至淡橙色固体

溶解性(25°C)

DMSO

≥25mg/ml

l  生物学信息

生物活性/药理作用

3-bromopyruvic acid is a 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is replaced by bromine. Synthetic brominated derivative and structural analog of pyruvic acid. Highly reactive alkylating agent. Anti-cancer drug It has a role as an alkylating agent and an antineoplastic agent. It is a 2-oxo monocarboxylic acid and an organobromine compound. It derives from a pyruvic acid. It is a conjugate acid of a 3-bromopyruvate.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov