产品名称

Salbutamol(沙丁胺醇)

一般描述

Salbutamol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP)

别 称

Albuterol; AH-3365; 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol 

纯 度

≥99.0%(HPLC)

CAS NO.

18559-94-9

分子式

C¹³H²¹NO³

分子量

239.31

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至黄色固体

溶解性(25°C)

DMSO

≥35mg/ml

l  生物学信息

生物活性/药理作用

Albuterol is a racemic mixture of the r-isomer levalbuterol and s-albuterol, a short-acting sympathomimetic agent with bronchodilator activity. Albuterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. Albuterol although to a lesser extent, also stimulates beta-1 adrenergic receptors, thereby increasing the force and rate of myocardial contraction.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov