产品名称

Glyceryl tridecanoate(三癸精)

一般描述

A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by capric (decanoic) acid.

别 称

Tricaprin; Tridecanoin; 2,3-di(decanoyloxy)propyl decanoate

纯 度

≥99.0%(GC)

CAS NO.

621-71-6

分子式

C³³H⁶²O⁶

分子量

554.84178

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

≥50mg/ml

l  生物学信息

生物活性/药理作用

Tricaprin is an orally available precursor of decanoic acid (DA), a 10-carbon fatty acid and major component of medium chain triglyceride oils, with potential antiandrogen and antihyperglycemic properties. Upon oral administration, tricaprin is hydrolyzed to DA, which binds to and partially activates peroxisome proliferator-activated receptor (PPAR)-gamma, as well as PPAR-alpha and PPAR-beta/delta, without inducing adipogenesis. Additionally, tricaprin may improve insulin sensitivity and decrease androgen production.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov