产品名称

Embelin

一般描述

Embelin, a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-ed inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.

别 称

Embelic Acid; NSC 91874; 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione

纯 度

≥98.5%(HPLC)

CAS NO.

550-24-3

分子式

C¹⁷H²⁶O⁴

分子量

294.39

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥45mg/ml

乙醇

≥5mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Embelin is a member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease. It has a role as a  hepatitis C protease inhibitor, an antimicrobial agent, an antineoplastic agent and a plant metabolite.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov