产品名称

Bromodeoxyuridine

一般描述

Bromodeoxyuridine is a nucleoside analog that competes with thymidine for incorporation into DNA, and used in the detection of proliferating cells.   

别 称

Broxuridine; 5-Bromodeoxyuridine; BrdU

纯 度

≥98.5%(HPLC)

CAS NO.

59-14-3

分子式

C⁹H¹¹BrN²O⁵

分子量

307.1

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至浅黄色固体

溶解性(25°C)

DMSO

≥50mg/ml

乙醇

~5mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Broxuridine is a halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov