Ixabepilone (BMS-247550)
商品编号：
TS3296
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-
TS3296-100MG
有货
12000
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+
备注：
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详细介绍
l 基本信息 |
产品名称 | Ixabepilone(伊沙匹隆) |
一般描述 | Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. |
别 称 | Azaepothilone B; Ixempra; BMS-247550 |
纯 度 | ≥97.0%(HPLC) | CAS NO. | 219989-84-1 |
分子式 | C27H42N2O5S | 分子量 | 506.7 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25°C) | DMSO | ≥50mg/ml |
乙醇 | ≥50mg/ml |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Ixabepilone is an orally bioavailable semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
