产品名称

Nootkatone((+)-香柏酮)      

一般描述

(+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities.

别 称

(4R,4aS,6R)-4,4a-dimethyl-6-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-one

纯 度

≥98.0%(GC)

CAS NO.

4674-50-4

分子式

C¹⁵H²²O

分子量

218.33458

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至淡黄色固体

l  生物学信息

生物活性/药理作用

Nootkatone has antiproliferative activity.Plant-derived acaricides nootkatone and carvacrol can suppress Ixodes scapularis Say and Amblyomma americanum (L.) (Acari: Ixodidae).(+)-Nootkatone has potent inhibitory effect on collagen-, thrombin-, and AA-induced platelet aggregation, it also has a significant inhibitory effect on rat platelet aggregation ex vivo. Nootkatone, a naturally occurring AMPK activator, can stimulate energy metabolism and prevents diet-induced obesity by activating AMPK.Nootkatone is a strong repellent and toxicant to Formosan subterranean termites, the lowest effective concentration tested is 10 micrograms/g substrate.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov