产品名称

(+)-Dipentene((R)-(+)-柠檬烯)

一般描述

(+)-Dipentene, occurring commonly in nature as the fragrance of oranges, is a flavoring agent in food manufacturing.

别 称

D-Limonene; (R)-(+)-Limonene; (+)-Carvene; (+)-(4R)-Limonene; Citrene; (4R)-1-methyl-4-prop-1-en-2-ylcyclohexene

纯 度

≥95.0%(GC)

CAS NO.

5989-27-5

分子式

C¹⁰H¹⁶

分子量

136.23404

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

液体

l  生物学信息

生物活性/药理作用

Limonene, (+)- is an oral dietary supplement containing a natural cyclic monoterpene and major component of the oil extracted from citrus peels with potential chemopreventive and antitumor activities. Although the mechanism of action has yet to be fully elucidated, limonene and its metabolites perillic acid, dihydroperillic acid, uroterpenol and limonene 1,2-diol may inhibit tumor growth through inhibition of p21-dependent signaling and may induce apoptosis via the induction of the transforming growth factor beta-signaling pathway. In addition, they inhibit post-translational modification of signal transduction proteins, resulting in G1 cell cycle arrest as well as differential  of cell cycle- and apoptosis-related genes.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov