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  • DNA Ligase from T4-infected Escherichia coli
    TS2972

    RO3280 is a potent, highly selective inhibitor of  Polo-like kinase 1 (PLK1) with IC50 of 3nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2975

    NMS-P937 is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3004

    TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor with IC50 of 20 nM, 200 nM, and 15 nM for Clk1, Clk2, and Clk4, respectively. No inhibitory effect on Clk3, SRPK1, SRPK2, or PKC.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3007

    ID-8 is a DYRK inhibitor, and sustains embryonic stem cell self-renewal in long-term culture.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3009

    6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C).  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3010

    K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3011

    K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3012

    K-Ras(G12C) inhibitor 6 is an allosteric, and selective inhibitor of oncogenic K-Ras(G12C).

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