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  • DNA Ligase from T4-infected Escherichia coli
    TS3145

    CAY10603 is a potent and selective HDAC6 inhibitor with IC50 of 2 pM, >200-fold selectivity over other HDACs.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3157

    Niraparib (MK-4827) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3159

    TH287 is a potent and selective MTH1 (NUDT1) inhibitor with IC50 of 0.8 nM.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3192

    BG45 is a class I HDAC inhibitor with IC50 of 289 nM, 2.0 nM, 2.2 nM and >20 nM for HDAC3, HDAC1, HDAC2, and HDAC6 in cell-free assays, respectively.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3200

    BMH-21 is a DNA intercalator, which binds ribosomal DNA and inhibits RNA polymerase I (Pol I) tranion.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3206

    BRD73954 is a potent and selective HDAC inhibitor with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3207

    NU1025 is a potent PARP inhibitor with IC50 of 400 nM.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3219

    6-thio-dG is a nucleoside analog and telomerase substrate.  

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