Nanocarrier CCG-222740 significantly decreased ACTA2 gene and was not cytotoxic in human conjunctival fibroblasts.
Theophylline(茶碱) is a nive phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.
BI-3406 is a potent, orally active and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with IC50 of 6 nM. BI-3406 reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling with anticancer activities.
Salbutamol Sulfate(硫酸沙丁胺醇) is a short-acting β2-adrenergic receptor agonist.
Sotalol HCl(索他洛尔盐酸盐) is a nive beta-adrenergic blocker used largely in the therapy cardiac arrhythmias.
Fingolimod HCl(盐酸芬戈莫德) is a S1P antagonist.
PF-543 is a novel sphingosine-competitive inhibitor of SphK1.
Dapagliflozin(达格列净) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.