Isoxicam(伊索昔康) is a non-steroidal anti-inflammatory drug that is not marketed in the United States.

SM 324405 was a potent TLR7 agonist (EC50 50 nM) and rapidly metabolized by human plasma (T1/2 2.6 min) to the pharmacologically much less active carboxylic acid.

Maraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES.

Pimecrolimus(吡美莫司) is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12 (FKBP-12); a calcineurin inhibitor.

Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.

MCC950 sodium salt is a potent, selective inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs; but not the AIM2, NLRC4 or NLRP1 inflammasomes.

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.

Febuxostat(非布索坦 ) is an orally available, non-purine inhibitor of xanthine oxidase with uric acid lowering activity.