Cobicistat is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM.
PF-4981517 is a potent and selective inhibitor of CYP3A4 (P450) with IC50 of 0.03 μM, exhibits >500-fold selectivity over CYP3A5 and CYP3A7.
Evacetrapib is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.
Aspirin(乙酰水杨酸) is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.
Pyridoxine HCl(吡哆醇盐酸盐) is a form of vitamin B6.
Vitamin C(维生素C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy.
Thiamine HCl( 维生素B1盐酸盐) is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes.
Moclobemide(吗氯贝胺) is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.