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  • DNA Ligase from T4-infected Escherichia coli
    TS3362

    Nutlin-3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3373

    Z-VAD(OH)-FMK is an irreversible pan-caspase inhibitor.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3377

    NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradation and p73 activation.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3410

    GSK481 is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3471

    GS-4997 is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3500

    WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activity of all four WNK family members (WNK1, WNK2, WNK3, and WNK4).

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  • DNA Ligase from T4-infected Escherichia coli
    TS3504

    CRT0066101 is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKCα/PKCβ/PKCε activity in multiple.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3513

    ML-7 HCL is an inhibitor of smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 μM and displays reversible, ATP-competitive inhibition of Ca2+-calmodulin-dependent and -independent smooth muscle MLCKs.

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