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  • DNA Ligase from T4-infected Escherichia coli
    TS2629

    Trimethyloctadecylammonium bromide(十八烷基三甲基溴化铵) is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin .

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  • DNA Ligase from T4-infected Escherichia coli
    TS2719

    H-Cys(Trt)-OH((+)-S-三苯甲基-L-半胱氨酸) is a specific inhibitor of Eg5 that inhibits Eg5-driven microtubule sliding velocity in a reversible fashion with an IC50 of 500 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2901

    GSK923295 is a first-in-class, specific allosteric inhibitor of CENP-E kinesin motor ATPase with Ki of 3.2 nM, and less potent to mutant I182 and T183.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2904

    IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM in a cell-free assay, no inhibition to group II PAKs (PAKs 4-6).

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  • DNA Ligase from T4-infected Escherichia coli
    TS2905

    HSP990 is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2915

    XL888 is an ATP-competitive inhibitor of HSP90 with IC50 of 24 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2939

    Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS2986

    HPOB is a potent, selective HDAC6 inhibitor with IC50 of 56 nM, >30-fold selectivity over other HDACs.  

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