Doxepin HCl(盐酸多塞平) is a tricyclic antidepressant formulated as a mixture of E-(trans) and Z-(cis) stereoisomers. It inhibits CYP2D6 activity in vivo.

Milnacipran(盐酸米那普仑) inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.

Darifenacin(氢溴酸达非那新) is a selective M3 muscarinic receptor antagonist with pKi of 8.9.

Tripelennamine(盐酸曲吡那敏) is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM.

Betahistine 2HCl(盐酸倍他司汀) is a histamine H3 receptor inhibitor with IC50 of 1.9 μM.

Amitriptyline HCl(盐酸阿米替林) inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.

Azatadine dimaleate(马来酸阿扎他啶) is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.

Ropinirole HCl(盐酸罗匹尼罗) a selective dopamine D2 receptors agonist with Ki of 29 nM.