ZLN005 is a potent and tissue-specific PGC-1α tranional activator.
FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
FPH1 (BRD-6125) is a small molecule, which promotes expansion of iPS-derived hepatocytes.
FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.
DDR1-IN-1 is a potent and selective discoidin domain receptor 1 (DDR1) receptor tyrosine kinase inhibitor with IC50 of 105 nM, about 3-fold selectivity over DDR2.
AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. It failed to inhibit PDHK4 at higher concentrations(>10 nM), AZD7545 stimulates PDHK4 activity.
BAPTA-AM is a selective, membrane-permeable calcium chelator.