Bupivacaine HCl(盐酸布比卡因) binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias.

Manidipine(马尼地平) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.

Nateglinide(那格列奈) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.

Propafenone HCl(盐酸普罗帕酮) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.

Phenytoin(苯妥英) is an inactive voltage-gated sodium channel stabilizer.

Ciclopirox(环吡酮胺) is a broad-spectrum antifungal agent working as an iron chelator.

Amiloride HCl dihydrate(盐酸阿米洛利二水合物) is a potent epithelial sodium channel (ENaC) blocker, used in the management of hypertension and congestive heart failure.

Gliclazide(格列齐特) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM.