Doxapram HCl(盐酸多沙普仑) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
Zinc pyrithione(2-巯基吡啶-N-氧化物锌盐) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Lomerizine dihydrochloride(盐酸洛美利嗪) is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.
Dexlansoprazole(右旋兰索拉唑), the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties.
Chlorocresol(4-氯-3-甲基苯酚) is an activator of ryanodine receptor.
Benzocaine(苯佐卡因) is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops.
Tenatoprazole(泰妥拉唑) is a prodrug of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 μM.
Mexiletine HCl(盐酸美西律) belongs to Class IB anti-arrhythmic group of medicines, inhibits sodium channels to reduce the inward sodium current.