23(S)-Me-LCA is a potent GP-BAR1 agonist which displayed an EC50 of 0.22 μM.
Palbociclib(帕博西尼) is an orally available highly selective inhibitor of CDK4/6 with potential antineoplastic activity.
Colchicine(秋水仙素), an alkaloid isolated from Colchicum autumnale, is a microtubule polymerization inhibitor with anti-gout and anti-inflammatory activities.
23(S)-Me-UDCA is a potent GP-BAR1 agonist which displayed an EC50 of 1.05 μM.
Y27632 dihydrochloride is a selective ROCK1 (p160ROCK) inhibitor.
Coptisine(氯化黄连碱), a cytotoxic alkaloid found in Chinese goldthread, has been analyzed as a cytotoxic agent in heptoma and leukemic cells and is reported to block cell cycle progression.
Pseudocoptisine chloride(盐酸异黄连碱) is a cytotoxic alkaloid found in Chinese goldthread
MK-1775 is a potent and selective Wee1 inhibitor.