PD184352 is an ATP non-competitive MEK1/2 inhibitor.

PD98059 is a non-ATP competitive MEK inhibitor.

BIX02189 is a selective inhibitor of MEK5.

Pimasertib is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.

Binimetinib is an orally available inhibitor of mitogen-activated protein kinase kinase 1 and 2 (MEK1/2) with potential antineoplastic activity.

Cobimetinib is an orally bioavailable small-molecule inhibitor of mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity.

PLX4720 is a potent and selective inhibitor of B-RafV600E.

GDC-0879 is a novel, potent, and selective B-Raf inhibitor.