5,6-Dehydroarachidonic acid inhibits 5-lipoxygenase of guinea pig leukocytes with an IC50 of 10 μM.
5-Lipoxygenase inhibitor; reduces thromboxane A2 production.
HZ52 is a dual inhibitor of mPGES and 5-lypoxygenase (Enzyme IC50 = 1.3 and 2.0 mM, respectively).
LY255283 is a competitive leukotriene B4 receptor antagonist, with an IC50 of about 100 nM.
NCTT-956 is a very potent, specific inhibitor of 12-lipoxygenase (12-LO) activity.
Potent cyclooxygenase and lipoxygenase inhibitor.
Potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy-PGDH).
Prostaglandin F2α analogue; thromboxane A2/prostaglandin H2 mimetic.