SC-57461A is an inhibitor of leukotriene A4 hydrolase.

Subtype-selective cysteinyl-leukotriene (Cys-Lt) antagonist.

Specific CysLT1 leukotriene receptor antagonist.

CysLT1 leukotriene receptor antagonist.

Quininib is a cell penetrant, potent and selective cysteinyl leukotriene receptor 1 and 2 (CysLT1-2) antagonist.

Prometastatic metabolite of arachidonic acid via the 12-lipoxygenase pathway that is expressed in many tumor cell lines. It is produced in coronary microvasculature and is a potent inducer of relaxation and hyperpolarization of these microvessels. It activates large-conductance Ca2+-activated K+ currents in coronary microvascular smooth muscle.

Metabolite of arachidonic acid via the 15-lipoxygenase pathway that may be involved in pulmonary anti-inflammatory responses through the inhibition of 5-lipoxygenase.

Arachidonic acid metabolite that stimulates epithelial cell migration during wound healing.