Costunolide is a germacranolide with anthelminthic, antiparasitic and antiviral activities.
TH588 is a potent and selective MTH1 (NUDT1) inhibitor.
Dacarbazine(达卡巴嗪) is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-s DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis used in the treatment of various cancers.
Dexrazoxane HCl (ICRF-187, ADR-529) is an intracellular iron chelator, which decreases the formation of superoxide radicals, used as a cardioprotective agent also an inhibitor of topoisomerase II
Altretamine(六甲蜜胺) is an anti-neoplastic agent.
Carmofur(卡莫氟) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.
Floxuridine(5-氟-2'-脱氧脲核苷) is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.
Mercaptopurine(6-巯基嘌呤) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.